etiology, pathogenesis

amoebae, pyogenic bacteria (streptococci, staphylococci, E. coli, Klebsiella), ascending cholangitis (stone obstruction, tumor, stricture), portal bacteraemia (diverticulitis, appendicitis), systemic bacteraemia from a distant site, direct biliary infestation, trauma

symptoms, signs

acute onset, fever, anorexia, nausea, weight loss, fatigue, palpable tenderness/pain in the right hypochondrium, hepatomegaly, jaundice (with biliary tract obstruction)

diagnostics

decreased values of Hb, Hct, albumin, leukocytosis, increased FW, increased values of ALP, bilirubin, positive blood cultures. Chest X-ray (basal pulmonary atelectasis, pleural effusion, pneumonia, diaphragm elevation), ultrasound examination, CT examination

complications

subphrenic abscess, bleeding into the abscess, rupture into lungs, pleural cavity and peritoneum

therapy - principles

surgical evacuation and drainage, systemic antimicrobial drugs